phosphorylation of proteins

phosphorylation of proteins
Addition of phosphate groups to hydroxyl groups on proteins (to the side chains of serine, threonine or tyrosine) catalysed by a protein kinase (often specific) with ATP as phosphate donor. Activity of proteins is often regulated by phosphorylation.

Dictionary of molecular biology. 2004.

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  • Phosphorylation — is the addition of a phosphate (PO4) group to a protein molecule or a small molecule. It can also be thought of as the introduction of a phosphate group into an organic molecule . Its prominent role in biochemistry is the subject of a very large… …   Wikipedia

  • Phosphorylation cascade — A phosphorylation cascade is a sequence of events where one enzyme phosphorylates another, causing a chain reaction leading to the phosphorylation of thousands of proteins.This can be seen in signal transduction of hormone… …   Wikipedia

  • Oxidative phosphorylation — The electron transport chain in the mitochondrion is the site of oxidative phosphorylation in eukaryotes. The NADH and succinate generated in the citric acid cycle are oxidized, releasing energy to power the ATP synthase. Oxidative… …   Wikipedia

  • Protein phosphorylation — is a post translational modification of proteins in which a serine, a threonine or a tyrosine reside is covalently modified by a protein kinase enzyme by the addition of a phosphate group. Regulation of proteins by phosphorylation is one of the… …   Wikipedia

  • Ccaat-enhancer-binding proteins — (or C/EBPs) are a family of transcription factors that are composed of six members C/EBP α to C/EBP ζ. They promote the expression of certain proteins through interaction with DNA.C/EBP proteins interact with the CCAAT (cytidine cytidine… …   Wikipedia

  • Intrinsically unstructured proteins — An ensemble of NMR structures of the Thylakoid soluble phosphoprotein TSP9, which shows a largely flexible protein chain.[1] Intrinsically unstructured proteins, often referred to as naturally unfolded proteins or disordered proteins, are… …   Wikipedia

  • FOX proteins — FOX (Forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic …   Wikipedia

  • high mobility group proteins — HMG proteins a highly conserved family of small nonhistone nucleoproteins that bind DNA and are involved in controlling transcription. They are important for growth and development, and are regulated by cell cycle–dependent phosphorylation.… …   Medical dictionary

  • protein phosphorylation — noun The binding of phosphate to proteins to form phosphoproteins …   Wiktionary

  • Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… …   Wikipedia

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